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Adenosine

Adenosine suppliers and sourcing guide

Adenosine is a nucleoside made of the base adenine joined to the sugar ribose. Commercial adenosine is made mainly by microbial fermentation, for example with Bacillus strains, followed by purification and crystallization. It is a white crystalline powder that is slightly soluble in cold water. Cosmetic brands buy it as a powder for the water phase of creams and serums, and pharmaceutical grades are made for injectable drugs.

See suppliersWhat to ask for on the COA
Also known as
9-beta-D-ribofuranosyladenine · 6-amino-9-beta-D-ribofuranosyl-9H-purine · CAS 58-61-7
Facts checked
November 2026

Forms and grades of adenosine

Suppliers sell different products under the same name. Specify the one you need.

  • Cosmetic-grade powder

    Crystalline adenosine sold for personal care.

  • Pharmacopeial grade

    Adenosine made to the USP or Ph. Eur. monograph, with tighter impurity limits.

  • Pre-dissolved solutions

    Adenosine at a stated concentration in water or glycol, which avoids slow dissolving.

What to check on the COA

Compare each result with your own specification when the lot arrives.

Assay (HPLC)
Adenosine content on the dried basis.
Related substances
Adenine, inosine and other nucleosides by HPLC.
Loss on drying
Water content of the powder.
Specific optical rotation
Identity and stereochemistry check.
Heavy metals and microbiology
Metals by ICP-MS and total aerobic count, yeast and mold.

Storage, lots and expiry

Storage and shelf life

Keep adenosine powder in sealed containers at room temperature, protected from moisture and light. It dissolves slowly in cold water, so plan warm dissolution in the water phase. Shelf life and retest dates come from the supplier.

Lots and expiry dates

Record assay and related substances for each lot and keep cosmetic and pharmacopeial grades apart. Use lots in order of receipt.

Regulatory status

Facts from regulators and standards bodies, each linked to its source.

This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.

Adenosine suppliers

Manufacturers and distributors whose own websites say they sell it.

We are checking adenosine suppliers now

Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.

Sell adenosine? Request a listing

Frequently asked questions

What forms of adenosine can brands buy?

Common forms include cosmetic-grade powder, pharmacopeial grade and pre-dissolved solutions. Ask each supplier for the specification sheet of the exact grade they quote.

What should the COA for adenosine include?

Expect assay (HPLC), related substances, loss on drying, specific optical rotation and heavy metals and microbiology, each with its method, specification and result for that lot.

How should adenosine be stored?

Keep adenosine powder in sealed containers at room temperature, protected from moisture and light. It dissolves slowly in cold water, so plan warm dissolution in the water phase. Shelf life and retest dates come from the supplier.

What is the regulatory status of adenosine?

Health Canada's Natural Health Products Ingredients Database lists adenosine (CAS 58-61-7) with the non-medicinal purpose skin-conditioning agent, for topical use only up to 1%, citing CIR. The same entry says adenosine or its salts are on the Prescription Drug List when sold or recommended for intravenous injection.

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