Copper bisglycinate
Copper bisglycinate is a chelate of one copper (II) ion with two molecules of the amino acid glycine. It is made by reacting a copper source such as copper hydroxide or carbonate with glycine in water, then drying the product to a blue powder. Brands buy it as powder, granules or branded chelates for tablets and capsules, often diluted, because copper is dosed in small amounts.
Suppliers sell different products under the same name. Specify the one you need.
The chelate with copper content stated on the specification.
Trademarked copper bisglycinate sold with the maker's chelation data.
Diluted on a carrier to a stated copper level for even dosing in small amounts.
Compare each result with your own specification when the lot arrives.
Store copper bisglycinate in tightly sealed containers in a cool, dry place away from light and moisture. Reseal opened packs to prevent caking. Shelf life is set by the supplier's specification, and aged stock is retested for copper and moisture.
Record the copper assay for each lot and calculate the dose from the actual result, since chelate copper content varies by maker. Keep supplier documentation for branded chelates with the lot record.
Facts from regulators and standards bodies, each linked to its source.
Health Canada's Multi-Vitamin/Mineral Supplements monograph for natural health products lists copper (II) bisglycinate among the source ingredients for copper (Table 2).
Source: webprod.hc-sc.gc.ca (opens in a new tab)21 CFR 101.9(c)(8)(iv) sets the Reference Daily Intake for copper at 0.9 mg for adults and children 4 years and older.
Source: ecfr.gov (opens in a new tab)This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Manufacturers and distributors whose own websites say they sell it.
Manufacturer · Bengaluru, India
Indian maker of pharmaceutical ingredients and mineral salts, with plants in Hosur. Its mineral range covers calcium, magnesium, iron, zinc, copper and selenium salts and amino acid chelates.
Suppliers are in alphabetical order and none pays to appear. Each claim is checked against the supplier’s own website on the date shown. Ask for the specification sheet and a recent COA before you order, and confirm details with the supplier.
Common forms include standard powder, branded chelates and triturations. Ask each supplier for the specification sheet of the exact grade they quote.
Expect copper assay, glycine content, identity and chelation, loss on drying and heavy metals and microbiology, each with its method, specification and result for that lot.
Store copper bisglycinate in tightly sealed containers in a cool, dry place away from light and moisture. Reseal opened packs to prevent caking. Shelf life is set by the supplier's specification, and aged stock is retested for copper and moisture.
Health Canada's Multi-Vitamin/Mineral Supplements monograph for natural health products lists copper (II) bisglycinate among the source ingredients for copper (Table 2). 21 CFR 101.9(c)(8)(iv) sets the Reference Daily Intake for copper at 0.9 mg for adults and children 4 years and older.
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