Copper gluconate
Copper gluconate suppliers and sourcing guide
Copper gluconate is the copper (II) salt of gluconic acid, made by reacting gluconic acid solutions with cupric oxide or basic cupric carbonate and then crystallizing or drying the product. It occurs as light blue to bluish-green crystals or a fine light blue powder that dissolves readily in water, with about 14% copper. Because copper doses are small, brands buy it as powder for premixes or as a diluted trituration for tablets and capsules.
- Category
- Vitamins and minerals
- Also known as
- Cupric gluconate · Copper (II) gluconate · CAS 527-09-3
- Facts checked
- November 2026
Forms and grades of copper gluconate
Suppliers sell different products under the same name. Specify the one you need.
USP or FCC powder
The standard soluble powder for premixes, drinks and tablets.
Triturations
Copper gluconate diluted on a carrier to a stated copper level for even dosing.
Granulated grades
Granules for direct compression.
What to check on the COA
Compare each result with your own specification when the lot arrives.
- Assay
- Copper gluconate content by iodometric titration or copper by ICP-OES, against the USP or Food Chemicals Codex specification.
- Identity
- Compendial tests for copper and gluconate.
- Reducing substances
- A limit test for reducing sugars and related impurities.
- Lead and other metals
- Lead, arsenic and cadmium by ICP-MS.
- Loss on drying
- Moisture of the powder.
Storage, lots and expiry
Storage and shelf life
Store copper gluconate in tightly closed containers in a cool, dry place away from moisture, which can cause caking. Keep it apart from strong reducing agents. Shelf life is set by the supplier's specification, and aged lots are retested for assay and moisture.
Lots and expiry dates
Record the copper assay for each lot and, for triturations, the dilution strength, since small assay shifts matter at milligram doses. Check color on receipt; a green shift can signal moisture exposure.
Regulatory status
Facts from regulators and standards bodies, each linked to its source.
21 CFR 184.1260 affirms copper gluconate as GRAS for use in food as a nutrient supplement and synergist at levels not exceeding current good manufacturing practice, and allows its use in infant formula.
Source: ecfr.gov (opens in a new tab)Health Canada's List of Food Additives with Other Accepted Uses permits copper gluconate in breath fresheners at up to 50 ppm.
Source: canada.ca (opens in a new tab)Health Canada's Multi-Vitamin/Mineral Supplements monograph for natural health products lists copper (II) gluconate among the source ingredients for copper (Table 2).
Source: webprod.hc-sc.gc.ca (opens in a new tab)21 CFR 101.9(c)(8)(iv) sets the Reference Daily Intake for copper at 0.9 mg for adults and children 4 years and older.
Source: ecfr.gov (opens in a new tab)
This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Copper gluconate suppliers
Manufacturers and distributors whose own websites say they sell it.
We are checking copper gluconate suppliers now
Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.
Sell copper gluconate? Request a listingFrequently asked questions
What forms of copper gluconate can brands buy?
Common forms include uSP or FCC powder, triturations and granulated grades. Ask each supplier for the specification sheet of the exact grade they quote.
What should the COA for copper gluconate include?
Expect assay, identity, reducing substances, lead and other metals and loss on drying, each with its method, specification and result for that lot.
How should copper gluconate be stored?
Store copper gluconate in tightly closed containers in a cool, dry place away from moisture, which can cause caking. Keep it apart from strong reducing agents. Shelf life is set by the supplier's specification, and aged lots are retested for assay and moisture.
What is the regulatory status of copper gluconate?
21 CFR 184.1260 affirms copper gluconate as GRAS for use in food as a nutrient supplement and synergist at levels not exceeding current good manufacturing practice, and allows its use in infant formula. Health Canada's List of Food Additives with Other Accepted Uses permits copper gluconate in breath fresheners at up to 50 ppm. Health Canada's Multi-Vitamin/Mineral Supplements monograph for natural health products lists copper (II) gluconate among the source ingredients for copper (Table 2). 21 CFR 101.9(c)(8)(iv) sets the Reference Daily Intake for copper at 0.9 mg for adults and children 4 years and older.
More vitamins and minerals
- Magnesium GlycinateMagnesium bisglycinate · Magnesium bisglycinate chelate
- Vitamin CL-ascorbic acid · Ascorbic acid
- Vitamin D3Cholecalciferol · Colecalciferol
- ZincZinc citrate · Zinc gluconate
- Vitamin A palmitateRetinyl palmitate · Retinol palmitate
- Vitamin A acetateRetinyl acetate · Retinol acetate
- Beta-caroteneβ-Carotene · all-trans-beta-carotene
- Vitamin D2Ergocalciferol · Calciferol
- Vitamin E (d-alpha tocopherol)d-alpha-tocopherol · RRR-alpha-tocopherol
- Mixed tocopherolsTocopherols concentrate, mixed · Mixed tocopherol concentrate
- Vitamin K1Phylloquinone · Phytonadione
- Vitamin K2 (MK-7)Menaquinone-7 · MK-7
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