Magnesium L-threonate
Magnesium L-threonate is the magnesium salt of L-threonic acid, a four-carbon sugar acid. L-threonic acid is typically produced by oxidizing ascorbic acid, and the acid is then reacted with a magnesium base such as magnesium carbonate or hydroxide, purified and dried to a white powder. It carries a low share of magnesium by weight (well under 10%), so doses are large relative to other magnesium salts; brands buy it as powder for capsules and drink mixes, often as a branded, patented ingredient.
Suppliers sell different products under the same name. Specify the one you need.
Patented ingredient supplied under a trade name with its own specification and use terms.
Magnesium L-threonate from other manufacturers, where stereochemistry and purity data deserve close review.
Agglomerated powder for better flow in capsule filling and tableting.
Compare each result with your own specification when the lot arrives.
Keep magnesium L-threonate in sealed containers in a cool, dry place away from light; it is hygroscopic and cakes when exposed to humid air. Reseal opened packs immediately. Shelf life is set by the supplier's stability data and specification, and older lots are retested for water and assay.
Record magnesium and L-threonate assays and water content for each lot. Because branded and generic material are both sold, keep supplier documentation on file and do not swap sources without a new specification review.
Facts from regulators and standards bodies, each linked to its source.
GRN 499, for magnesium L-threonate hydrate notified by Magceutics, Inc. as a source of dietary magnesium in certain food categories, closed on September 3, 2014 with FDA having no questions.
Source: hfpappexternal.fda.gov (opens in a new tab)Health Canada's Multi-Vitamin/Mineral Supplements monograph for natural health products lists magnesium L-threonate among the source ingredients for magnesium (Table 2).
Source: webprod.hc-sc.gc.ca (opens in a new tab)This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Manufacturers and distributors whose own websites say they sell it.
Distributor · City of Industry, CA
Sells it as Magtein
California ingredient supplier that sources branded and commodity ingredients for supplement and food makers, from amino acids and vitamins to magnesium L-threonate and a plant-based vitamin D3.
Manufacturer · Bengaluru, India
Indian maker of pharmaceutical ingredients and mineral salts, with plants in Hosur. Its mineral range covers calcium, magnesium, iron, zinc, copper and selenium salts and amino acid chelates.
Suppliers are in alphabetical order and none pays to appear. Each claim is checked against the supplier’s own website on the date shown. Ask for the specification sheet and a recent COA before you order, and confirm details with the supplier.
Common forms include branded powder, generic powder and granulated grades. Ask each supplier for the specification sheet of the exact grade they quote.
Expect magnesium assay, l-threonate assay and identity, related substances, loss on drying or water and heavy metals and microbiology, each with its method, specification and result for that lot.
Keep magnesium L-threonate in sealed containers in a cool, dry place away from light; it is hygroscopic and cakes when exposed to humid air. Reseal opened packs immediately. Shelf life is set by the supplier's stability data and specification, and older lots are retested for water and assay.
GRN 499, for magnesium L-threonate hydrate notified by Magceutics, Inc. as a source of dietary magnesium in certain food categories, closed on September 3, 2014 with FDA having no questions. Health Canada's Multi-Vitamin/Mineral Supplements monograph for natural health products lists magnesium L-threonate among the source ingredients for magnesium (Table 2).
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