Tranexamic acid
Tranexamic acid suppliers and sourcing guide
Tranexamic acid is trans-4-(aminomethyl)cyclohexanecarboxylic acid, a synthetic analog of the amino acid lysine. It is made by chemical synthesis and purified to the trans isomer, and is sold as a white crystalline powder that dissolves freely in water. Most production is to pharmacopeial grades for prescription drug products; cosmetic buyers purchase the same powder or derivatives such as cetyl tranexamate.
- Category
- Cosmetic actives
- Also known as
- trans-4-(aminomethyl)cyclohexanecarboxylic acid · TXA · CAS 1197-18-8
- Facts checked
- November 2026
Forms and grades of tranexamic acid
Suppliers sell different products under the same name. Specify the one you need.
Pharmacopeial powder (USP, Ph. Eur., JP)
White crystalline powder made to a pharmacopeial monograph, the form most suppliers sell.
Cosmetic grade powder
Tranexamic acid sold for personal care, sometimes to an in-house specification rather than a pharmacopeia; ask which standard applies.
Ester derivatives
Derivatives such as cetyl tranexamate, separate ingredients with their own INCI names and specifications.
What to check on the COA
Compare each result with your own specification when the lot arrives.
- Assay (titration or HPLC)
- Tranexamic acid content by titration or HPLC on a dried basis.
- Related compounds (HPLC)
- The cis isomer and other synthesis impurities by HPLC, each with a pharmacopeial limit.
- Identity (IR)
- Infrared spectrum against a reference standard.
- Loss on drying and residue on ignition
- Moisture and inorganic residue.
- Heavy metals
- Lead and other metals by ICP-MS against the monograph or supplier limit.
Storage, lots and expiry
Storage and shelf life
Tranexamic acid powder is stable; keep it in a tightly closed container at controlled room temperature, protected from moisture. Shelf life and retest dates are set by the supplier, usually from pharmacopeial stability data.
Lots and expiry dates
Record the assay, cis-isomer result and the pharmacopeia each lot is tested to. Keep pharmaceutical and cosmetic-only grades separate if both are stocked.
Regulatory status
Facts from regulators and standards bodies, each linked to its source.
An FDA-hosted label for tranexamic acid tablets, for oral use, gives an initial U.S. approval of 1986.
Source: nctr-crs.fda.gov (opens in a new tab)The same label gives the chemical name trans-4-aminomethyl-cyclohexanecarboxylic acid and describes tranexamic acid USP as a white crystalline powder, freely soluble in water.
Source: nctr-crs.fda.gov (opens in a new tab)
This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Tranexamic acid suppliers
Manufacturers and distributors whose own websites say they sell it.
We are checking tranexamic acid suppliers now
Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.
Sell tranexamic acid? Request a listingFrequently asked questions
What forms of tranexamic acid can brands buy?
Common forms include pharmacopeial powder (USP, Ph. Eur., JP), cosmetic grade powder and ester derivatives. Ask each supplier for the specification sheet of the exact grade they quote.
What should the COA for tranexamic acid include?
Expect assay (titration or HPLC), related compounds (HPLC), identity (IR), loss on drying and residue on ignition and heavy metals, each with its method, specification and result for that lot.
How should tranexamic acid be stored?
Tranexamic acid powder is stable; keep it in a tightly closed container at controlled room temperature, protected from moisture. Shelf life and retest dates are set by the supplier, usually from pharmacopeial stability data.
What is the regulatory status of tranexamic acid?
An FDA-hosted label for tranexamic acid tablets, for oral use, gives an initial U.S. approval of 1986. The same label gives the chemical name trans-4-aminomethyl-cyclohexanecarboxylic acid and describes tranexamic acid USP as a white crystalline powder, freely soluble in water.
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