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Akkermansia muciniphila

Akkermansia muciniphila suppliers and sourcing guide

Akkermansia muciniphila is a strictly anaerobic, mucin-degrading bacterium first isolated from human feces in 2004. It is grown by anaerobic fermentation, which makes production harder than for lactic acid bacteria. It is sold in two forms: live freeze-dried cells, which need oxygen-free handling and packaging, and pasteurized (heat-inactivated) cells, the form authorized as a novel food in the EU. Buyers specify the form, the strain and how quantity is stated: CFU for live cells, total cell count for pasteurized.

See suppliersWhat to ask for on the COA
Also known as
A. muciniphila · pasteurized Akkermansia muciniphila
Facts checked
November 2026

Forms and grades of akkermansia muciniphila

Suppliers sell different products under the same name. Specify the one you need.

  • Live freeze-dried cells

    Viable cells at a stated CFU per gram, packed under nitrogen or in oxygen-barrier packs because the organism does not tolerate oxygen.

  • Pasteurized cells

    Heat-inactivated biomass sold by total cell count per gram rather than CFU; a different ingredient from the live form, with its own documentation.

  • Named strain

    A specific strain identified by a deposit number or trade designation, sold with that strain's own documentation; the strain belongs on the specification.

  • Multi-strain blend

    Pre-blended with other strains or fibers in finished-format powders; ask for a separate count for each organism.

What to check on the COA

Compare each result with your own specification when the lot arrives.

Count
Viable count by anaerobic plating for live material, or total cell count by flow cytometry or qPCR for pasteurized material, reported per gram against a minimum.
Identity
Species and strain confirmed by 16S rRNA gene sequencing and whole-genome sequencing against the deposited strain.
Inactivation check
For pasteurized material, no growth of A. muciniphila from a stated sample, confirming the heat step worked.
Contaminant microbiology
Enterobacteriaceae, E. coli, Staphylococcus aureus, yeast and mold, and absence of Salmonella and Listeria monocytogenes in a stated sample size.
Water activity or moisture
Held to a low maximum, since moisture shortens shelf life for both forms.
Heavy metals
Lead, arsenic, cadmium and mercury by ICP-MS against the supplier's specification.

Storage, lots and expiry

Storage and shelf life

Live material is kept frozen or refrigerated in sealed oxygen-barrier packs, often nitrogen-flushed with an oxygen absorber, and is opened only briefly. Pasteurized material is more stable and is usually stored sealed, cool and dry as the supplier specifies. Shelf life is set by the supplier from count stability data, and aged live stock is retested before use.

Lots and expiry dates

Record the count, its method (CFU or total cells) and the strain for each lot, and do not substitute one form for the other, since the counts are not comparable. Rotate stock FEFO.

Regulatory status

Facts from regulators and standards bodies, each linked to its source.

  • The EU Novel Food Catalogue entry for Akkermansia muciniphila (POL-NF-16941) gives it the status authorised novel food for the pasteurised form.

    Source: ec.europa.eu (opens in a new tab)

  • FDA's list of recently updated new dietary ingredient notifications it has reviewed includes NDIN 1438, pasteurized Akkermansia muciniphila HB05P from HealthBiome Inc.; the list does not state the content of FDA's response.

    Source: fda.gov (opens in a new tab)

This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.

Akkermansia muciniphila suppliers

Manufacturers and distributors whose own websites say they sell it.

We are checking akkermansia muciniphila suppliers now

Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.

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Frequently asked questions

What forms of akkermansia muciniphila can brands buy?

Common forms include live freeze-dried cells, pasteurized cells, named strain and multi-strain blend. Ask each supplier for the specification sheet of the exact grade they quote.

What should the COA for akkermansia muciniphila include?

Expect count, identity, inactivation check, contaminant microbiology, water activity or moisture and heavy metals, each with its method, specification and result for that lot.

How should akkermansia muciniphila be stored?

Live material is kept frozen or refrigerated in sealed oxygen-barrier packs, often nitrogen-flushed with an oxygen absorber, and is opened only briefly. Pasteurized material is more stable and is usually stored sealed, cool and dry as the supplier specifies. Shelf life is set by the supplier from count stability data, and aged live stock is retested before use.

What is the regulatory status of akkermansia muciniphila?

The EU Novel Food Catalogue entry for Akkermansia muciniphila (POL-NF-16941) gives it the status authorised novel food for the pasteurised form. FDA's list of recently updated new dietary ingredient notifications it has reviewed includes NDIN 1438, pasteurized Akkermansia muciniphila HB05P from HealthBiome Inc.; the list does not state the content of FDA's response.

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