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Citrus bioflavonoids

Citrus bioflavonoids suppliers and sourcing guide

Citrus bioflavonoids are mixed flavonoid extracts from the peel and pulp of oranges, grapefruit, lemons, limes and tangerines. Depending on the fruit, the mix is dominated by hesperidin, naringin, eriocitrin or neohesperidin, along with smaller amounts of other flavonoids. Peel is extracted with water or water-alcohol, then concentrated and dried, and the powder is sold standardized to a total bioflavonoid percentage or to a lead flavonoid such as hesperidin.

See suppliersWhat to ask for on the COA
Also known as
Citrus flavonoids · Bioflavonoid complex · Citrus peel extract
Facts checked
November 2026

Forms and grades of citrus bioflavonoids

Suppliers sell different products under the same name. Specify the one you need.

  • Standardized citrus bioflavonoid complex

    Mixed citrus flavonoids sold at a declared total bioflavonoid percentage; the test method behind that number varies between suppliers.

  • Orange-sourced (hesperidin-rich)

    Sweet orange extracts where hesperidin is the main flavonoid.

  • Lemon bioflavonoids

    Lemon extracts with eriocitrin and hesperidin as the main flavonoids.

  • Grapefruit-sourced (naringin-rich)

    Grapefruit extracts where naringin is the main flavonoid.

  • Blends with vitamin C

    Premixes of citrus bioflavonoids with ascorbic acid at stated ratios.

What to check on the COA

Compare each result with your own specification when the lot arrives.

Total bioflavonoids
Total flavonoid content by UV spectrophotometry or by summing HPLC peaks; ask which method is used, because results from the two are not interchangeable.
Flavonoid profile (HPLC)
Individual flavonoids such as hesperidin, naringin, eriocitrin and neohesperidin, which confirm the citrus source.
Loss on drying
Moisture, which affects caking and the assay basis.
Pesticide residues
Multi-residue screen, since peel concentrates residues from the fruit.
Heavy metals
Lead, arsenic, cadmium and mercury by ICP-MS.
Microbiology
Total plate count, yeast and mold, and pathogens.

Storage, lots and expiry

Storage and shelf life

Keep citrus bioflavonoid powders sealed in a cool, dry place away from light; they are hygroscopic and cake once opened. Shelf life and retest dates come from the supplier's specification.

Lots and expiry dates

The flavonoid profile shifts with fruit variety, harvest and supplier, so record total bioflavonoids and the main flavonoid percentages for each lot. Keep the citrus species on lot records if your label names it.

Regulatory status

Facts from regulators and standards bodies, each linked to its source.

  • Health Canada's citrus bioflavonoids monograph for natural health products lists the fruit and fruit peel of Citrus aurantiifolia, Citrus limon, Citrus paradisi, Citrus reticulata and Citrus sinensis as source materials.

    Source: webprod.hc-sc.gc.ca (opens in a new tab)

  • The same monograph sets a maximum of 600 milligrams of citrus bioflavonoids per day for adults, including when combined with other bioflavonoids such as quercetin, hesperidin or rutin.

    Source: webprod.hc-sc.gc.ca (opens in a new tab)

This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.

Citrus bioflavonoids suppliers

Manufacturers and distributors whose own websites say they sell it.

We are checking citrus bioflavonoids suppliers now

Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.

Sell citrus bioflavonoids? Request a listing

Frequently asked questions

What forms of citrus bioflavonoids can brands buy?

Common forms include standardized citrus bioflavonoid complex, orange-sourced (hesperidin-rich), lemon bioflavonoids, grapefruit-sourced (naringin-rich) and blends with vitamin C. Ask each supplier for the specification sheet of the exact grade they quote.

What should the COA for citrus bioflavonoids include?

Expect total bioflavonoids, flavonoid profile (HPLC), loss on drying, pesticide residues, heavy metals and microbiology, each with its method, specification and result for that lot.

How should citrus bioflavonoids be stored?

Keep citrus bioflavonoid powders sealed in a cool, dry place away from light; they are hygroscopic and cake once opened. Shelf life and retest dates come from the supplier's specification.

What is the regulatory status of citrus bioflavonoids?

Health Canada's citrus bioflavonoids monograph for natural health products lists the fruit and fruit peel of Citrus aurantiifolia, Citrus limon, Citrus paradisi, Citrus reticulata and Citrus sinensis as source materials. The same monograph sets a maximum of 600 milligrams of citrus bioflavonoids per day for adults, including when combined with other bioflavonoids such as quercetin, hesperidin or rutin.

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