Ubiquinol
Ubiquinol is the reduced form of coenzyme Q10, made commercially by chemically reducing CoQ10 (usually from fermentation) and then isolating it under conditions that keep oxygen out. It converts back to ubiquinone when exposed to air, heat or light, so it is supplied mainly as crystalline ubiquinol packed under inert gas or already dispersed in oil for softgels. Brands usually buy it as a softgel-ready concentrate or a stabilized powder from a small number of producers.
Suppliers sell different products under the same name. Specify the one you need.
Pure ubiquinol powder shipped in nitrogen-flushed, light-proof packaging, mostly used by softgel makers who blend it into oil themselves.
Ubiquinol pre-dissolved in a carrier oil, sometimes with a stabilizer, ready for softgel encapsulation.
Ubiquinol encapsulated or coated with carriers for capsules and tablets; the coating limits contact with oxygen and lowers the ubiquinol percentage per gram.
Compare each result with your own specification when the lot arrives.
Keep ubiquinol in its original sealed, nitrogen-flushed and light-proof packaging, and follow the supplier's temperature instructions, which commonly call for cold storage. Once a container is opened, oxidation to ubiquinone starts, so use it quickly or reseal under inert gas. Shelf life is set by the supplier's specification and confirmed by retesting ubiquinol and ubiquinone content.
Record ubiquinol and ubiquinone results for each lot and recheck older or opened stock before use, because the ratio shifts with time and exposure. Rotate strictly first-expired, first-out.
Facts from regulators and standards bodies, each linked to its source.
Health Canada has a natural health product monograph for ubiquinol that lists it as a synthetic medicinal ingredient for oral use.
Source: webprod.hc-sc.gc.ca (opens in a new tab)This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Manufacturers and distributors whose own websites say they sell it.
Manufacturer · Pasadena, TX
Sells it as Kaneka Ubiquinol
Texas-based division of Kaneka North America that makes yeast-fermented CoQ10 in two forms, ubiquinol and ubiquinone, for supplement brands and formulators.
Suppliers are in alphabetical order and none pays to appear. Each claim is checked against the supplier’s own website on the date shown. Ask for the specification sheet and a recent COA before you order, and confirm details with the supplier.
Common forms include crystalline ubiquinol, oil-based concentrate and stabilized powder. Ask each supplier for the specification sheet of the exact grade they quote.
Expect ubiquinol assay (HPLC), ubiquinone content, identity, residual solvents, heavy metals and microbiology, each with its method, specification and result for that lot.
Keep ubiquinol in its original sealed, nitrogen-flushed and light-proof packaging, and follow the supplier's temperature instructions, which commonly call for cold storage. Once a container is opened, oxidation to ubiquinone starts, so use it quickly or reseal under inert gas. Shelf life is set by the supplier's specification and confirmed by retesting ubiquinol and ubiquinone content.
Health Canada has a natural health product monograph for ubiquinol that lists it as a synthetic medicinal ingredient for oral use.
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