Skip to content
SupplyList
Menu

Crospovidone

Crospovidone suppliers and sourcing guide

Crospovidone is a cross-linked, water-insoluble form of polyvinylpyrrolidone made by polymerizing N-vinyl-2-pyrrolidone under conditions that build a cross-linked network. It swells quickly in water without dissolving or forming a gel. Tablet makers buy it as a fast-acting disintegrant and binder, and beverage makers use food grades (often called PVPP) to remove polyphenols from beer, wine and juice before filtering it out.

See suppliersWhat to ask for on the COA
Also known as
Polyvinylpolypyrrolidone · PVPP · Cross-linked povidone · E1202
Facts checked
November 2026

Forms and grades of crospovidone

Suppliers sell different products under the same name. Specify the one you need.

  • Type A and Type B

    Pharmacopeial monographs distinguish two types that differ mainly in particle size; coarser grades break tablets apart faster and finer grades give smoother surfaces.

  • Fine and micronized grades

    Small-particle grades for small tablets, orally dispersible tablets and suspensions.

  • Beverage-grade PVPP

    Grades for clarifying beer, wine, juice and vinegar, offered for single use or for regeneration and reuse.

What to check on the COA

Compare each result with your own specification when the lot arrives.

Identity
IR spectrum compared with a reference standard.
Nitrogen content (assay)
Nitrogen by Kjeldahl or combustion, reported on a dry basis against the monograph range.
Water-soluble substances
The fraction that dissolves in water, which limits soluble povidone and low-molecular-weight material.
Monomer and peroxides
Residual N-vinyl-2-pyrrolidone by HPLC and peroxides by titration or colorimetry.
Loss on drying
Moisture; crospovidone is hygroscopic and picks up water once opened.
Particle size
Laser diffraction or sieve analysis, which affects disintegration time and tablet appearance.

Storage, lots and expiry

Storage and shelf life

Keep tightly closed in a dry place, because the powder absorbs moisture from air and then performs less consistently. Shelf life or retest date is set by the supplier; reseal opened containers promptly and retest moisture on older stock.

Lots and expiry dates

Particle size and moisture vary by lot and change disintegration time and flow. Record type (A or B), particle size and peroxide value per lot, especially for formulas with oxidation-sensitive actives.

Regulatory status

Facts from regulators and standards bodies, each linked to its source.

  • 21 CFR 173.50 permits polyvinylpolypyrrolidone, an insoluble cross-linked homopolymer of vinylpyrrolidone, as a clarifying agent in beverages and vinegar, followed by removal by filtration.

    Source: ecfr.gov (opens in a new tab)

  • FDA's Substances Added to Food inventory lists polyvinyl polypyrrolidone, with crospovidone as another name, under the technical effects processing aid and surface-finishing agent, citing 21 CFR 173.50.

    Source: hfpappexternal.fda.gov (opens in a new tab)

  • Health Canada's Natural Health Products Ingredients Database lists crospovidone with non-medicinal purposes including binder, clarifying agent and disintegrant.

    Source: webprod.hc-sc.gc.ca (opens in a new tab)

This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.

Crospovidone suppliers

Manufacturers and distributors whose own websites say they sell it.

We are checking crospovidone suppliers now

Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.

Sell crospovidone? Request a listing

Frequently asked questions

What forms of crospovidone can brands buy?

Common forms include type A and Type B, fine and micronized grades and beverage-grade PVPP. Ask each supplier for the specification sheet of the exact grade they quote.

What should the COA for crospovidone include?

Expect identity, nitrogen content (assay), water-soluble substances, monomer and peroxides, loss on drying and particle size, each with its method, specification and result for that lot.

How should crospovidone be stored?

Keep tightly closed in a dry place, because the powder absorbs moisture from air and then performs less consistently. Shelf life or retest date is set by the supplier; reseal opened containers promptly and retest moisture on older stock.

What is the regulatory status of crospovidone?

21 CFR 173.50 permits polyvinylpolypyrrolidone, an insoluble cross-linked homopolymer of vinylpyrrolidone, as a clarifying agent in beverages and vinegar, followed by removal by filtration. FDA's Substances Added to Food inventory lists polyvinyl polypyrrolidone, with crospovidone as another name, under the technical effects processing aid and surface-finishing agent, citing 21 CFR 173.50. Health Canada's Natural Health Products Ingredients Database lists crospovidone with non-medicinal purposes including binder, clarifying agent and disintegrant.

More starches, carriers and excipients

All 37 starches, carriers and excipients

Sell ingredients to brands?

Request a free listing for the ingredients you make or distribute. No paid placement.

Request a listing