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Huperzine A

Huperzine A suppliers and sourcing guide

Huperzine A is an alkaloid found in the club moss Huperzia serrata and related species. It is made by extracting the dried whole plant, then purifying to a standardized extract or to near-pure huperzine A; synthetic huperzine A is also offered. Because daily amounts are in micrograms, brands usually buy it diluted, for example as a 1% extract or a 1% trituration on a carrier, rather than as pure material.

See suppliersWhat to ask for on the COA
Also known as
Huperzia serrata extract · toothed clubmoss extract · selagine · Qian Ceng Ta
Facts checked
November 2026

Forms and grades of huperzine A

Suppliers sell different products under the same name. Specify the one you need.

  • Standardized Huperzia serrata extract

    Plant extract standardized to a stated huperzine A percentage, commonly 1% or lower.

  • Purified huperzine A (98%)

    Near-pure isolate, sold for further dilution by the buyer or a toll blender.

  • Diluted triturations

    Purified huperzine A blended onto a carrier at 1% or 0.1% so microgram doses can be weighed and blended evenly.

  • Synthetic huperzine A

    Made by chemical synthesis; source and stereochemistry should be declared on the specification.

What to check on the COA

Compare each result with your own specification when the lot arrives.

Huperzine A assay (HPLC)
Huperzine A content by HPLC against a reference standard; the COA should state the method.
Identity
HPLC retention time or HPTLC fingerprint for extracts; IR or NMR for purified material.
Blend uniformity
For triturations, content uniformity across samples, since the active is a small fraction of the blend.
Residual solvents
Ethanol or other extraction solvents against USP <467> or the buyer's limits.
Heavy metals
Lead, arsenic, cadmium and mercury by ICP-MS, checked against the supplier specification and the buyer's own limits.
Microbiology
Total plate count, yeast and mold, coliforms or E. coli, and Salmonella, against the supplier specification.

Storage, lots and expiry

Storage and shelf life

Store sealed, cool, dry and protected from light. Purified huperzine A is potent at microgram levels, so keep it in clearly labeled, controlled storage separate from bulk ingredients. Shelf life and retest date come from the supplier, with the assay repeated at retest.

Lots and expiry dates

Because doses are in micrograms, record the exact assay and dilution of each lot and recalculate batch amounts when lots change. Keep dilutions and purified material traceable to finished batches and rotate first-expiry-first-out.

Regulatory status

Facts from regulators and standards bodies, each linked to its source.

This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.

Huperzine A suppliers

Manufacturers and distributors whose own websites say they sell it.

We are checking huperzine A suppliers now

Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.

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Frequently asked questions

What forms of huperzine A can brands buy?

Common forms include standardized Huperzia serrata extract, purified huperzine A (98%), diluted triturations and synthetic huperzine A. Ask each supplier for the specification sheet of the exact grade they quote.

What should the COA for huperzine A include?

Expect huperzine A assay (HPLC), identity, blend uniformity, residual solvents, heavy metals and microbiology, each with its method, specification and result for that lot.

How should huperzine A be stored?

Store sealed, cool, dry and protected from light. Purified huperzine A is potent at microgram levels, so keep it in clearly labeled, controlled storage separate from bulk ingredients. Shelf life and retest date come from the supplier, with the assay repeated at retest.

What is the regulatory status of huperzine A?

A Health Canada multi-ingredient natural health product monograph lists huperzine A as a medicinal ingredient, with the dried whole plant of Huperzia serrata as a source material. The same monograph gives a dose of up to 200 micrograms of huperzine A per day, and when Huperzia serrata extract and huperzine A are combined, the total huperzine A in the product cannot exceed 200 micrograms per day. The monograph limits standardized Huperzia serrata extracts to up to 20 milligrams of extract per day, at no more than 1% huperzine A potency.

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