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Theacrine

Theacrine suppliers and sourcing guide

Theacrine (1,3,7,9-tetramethyluric acid) is a purine alkaloid related to caffeine, found in the leaves of kucha, a tea plant variety from southern China, and in cupuacu (Theobroma grandiflorum). Most commercial theacrine is made by chemical synthesis and purified to a white crystalline powder, and much of it is sold as branded ingredients. Diluted and pre-blended grades are offered because amounts per serving are small.

Also known as
1,3,7,9-tetramethyluric acid · 7,9-dihydro-1,3,7,9-tetramethyl-1H-purine-2,6,8(3H)-trione · CAS 2309-49-1
Facts checked
November 2026

Forms and grades of theacrine

Suppliers sell different products under the same name. Specify the one you need.

  • Purified theacrine

    Crystalline powder of high purity, the usual traded form.

  • Branded ingredients

    Theacrine sold under a trademark with use terms and supplier documentation.

  • Diluted blends

    Theacrine on a carrier at a stated percentage so small amounts blend evenly.

  • Plant-derived theacrine

    Theacrine from tea leaf, offered by fewer suppliers; the source should be stated on the specification.

What to check on the COA

Compare each result with your own specification when the lot arrives.

Assay (HPLC)
Theacrine purity by HPLC against a reference standard.
Related substances
Caffeine and other methylxanthines or methyluric acids by HPLC.
Identity
IR or NMR spectrum and HPLC retention time.
Residual solvents
Solvents from synthesis, extraction or crystallization, against USP <467> or the buyer's limits.
Heavy metals
Lead, arsenic, cadmium and mercury by ICP-MS, checked against the supplier specification and the buyer's own limits.
Microbiology
Total plate count, yeast and mold, coliforms or E. coli, and Salmonella, against the supplier specification.

Storage, lots and expiry

Storage and shelf life

Store sealed in a cool, dry place protected from light. Keep pure material in clearly labeled, controlled storage. Shelf life and retest date are set by the supplier's specification.

Lots and expiry dates

Record assay, source (synthetic or plant) and any dilution for each lot, and recalculate batch amounts when switching grades. Rotate first-expiry-first-out.

Regulatory status

Facts from regulators and standards bodies, each linked to its source.

This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.

Theacrine suppliers

Manufacturers and distributors whose own websites say they sell it.

We are checking theacrine suppliers now

Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.

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Frequently asked questions

What forms of theacrine can brands buy?

Common forms include purified theacrine, branded ingredients, diluted blends and plant-derived theacrine. Ask each supplier for the specification sheet of the exact grade they quote.

What should the COA for theacrine include?

Expect assay (HPLC), related substances, identity, residual solvents, heavy metals and microbiology, each with its method, specification and result for that lot.

How should theacrine be stored?

Store sealed in a cool, dry place protected from light. Keep pure material in clearly labeled, controlled storage. Shelf life and retest date are set by the supplier's specification.

What is the regulatory status of theacrine?

Health Canada's Natural Health Products Ingredients Database lists theacrine as an approved chemical name, with tea (Camellia sinensis) leaf and Theobroma grandiflorum fruit as source materials. The same entry classifies theacrine as an isolate under Schedule 1, item 2 of the Natural Health Products Regulations.

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