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Urolithin A

Urolithin A suppliers and sourcing guide

Urolithin A is a dibenzopyranone formed by gut bacteria from ellagitannins and ellagic acid, which occur in foods such as pomegranates, walnuts and berries. Because the amount formed from food varies widely between people, ingredient suppliers make urolithin A directly by chemical synthesis and purify it to a high-purity off-white powder. Supply is concentrated among a few manufacturers, some with patents and branded grades.

See suppliersWhat to ask for on the COA
Also known as
3,8-dihydroxy-6H-dibenzo[b,d]pyran-6-one · 3,8-dihydroxyurolithin · CAS 1143-70-0
Facts checked
November 2026

Forms and grades of urolithin A

Suppliers sell different products under the same name. Specify the one you need.

  • Synthetic urolithin A

    High-purity crystalline powder, the main traded form.

  • Branded ingredients

    Urolithin A sold under a trademark with supplier dossiers and use terms.

  • Micronized grades

    Fine particle powder for better dispersion in drinks and softgels.

  • Pomegranate or ellagitannin extracts

    Extracts of the precursors, not urolithin A itself; label them as the extract.

What to check on the COA

Compare each result with your own specification when the lot arrives.

Assay (HPLC)
Urolithin A purity by HPLC against a reference standard.
Related substances
Synthesis intermediates and other urolithins by HPLC.
Identity
IR or NMR spectrum and HPLC retention time.
Residual solvents
Solvents from synthesis and crystallization, against USP <467> or the buyer's limits.
Particle size
Laser diffraction for micronized grades.
Heavy metals
Lead, arsenic, cadmium and mercury by ICP-MS, checked against the supplier specification and the buyer's own limits.

Storage, lots and expiry

Storage and shelf life

Store sealed in a cool, dry place protected from light. Keep purified material in labeled, controlled storage. Shelf life and retest date come from the supplier's specification.

Lots and expiry dates

Record assay and particle size grade for each lot, and keep supplier dossiers and any license terms in the lot file. Rotate first-expiry-first-out.

Regulatory status

Facts from regulators and standards bodies, each linked to its source.

  • FDA's GRAS Notice Inventory lists GRN 791 for urolithin A, notified by Amazentis SA for use in protein shakes, meal replacement beverages, oatmeal, bars and yogurts; it closed on December 20, 2018 with FDA having no questions.

    Source: hfpappexternal.fda.gov (opens in a new tab)

  • Health Canada's Natural Health Products Ingredients Database lists urolithin A as an approved chemical name, with a non-medicinal role as a skin-conditioning agent for topical use only.

    Source: webprod.hc-sc.gc.ca (opens in a new tab)

This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.

Urolithin A suppliers

Manufacturers and distributors whose own websites say they sell it.

We are checking urolithin A suppliers now

Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.

Sell urolithin A? Request a listing

Frequently asked questions

What forms of urolithin A can brands buy?

Common forms include synthetic urolithin A, branded ingredients, micronized grades and pomegranate or ellagitannin extracts. Ask each supplier for the specification sheet of the exact grade they quote.

What should the COA for urolithin A include?

Expect assay (HPLC), related substances, identity, residual solvents, particle size and heavy metals, each with its method, specification and result for that lot.

How should urolithin A be stored?

Store sealed in a cool, dry place protected from light. Keep purified material in labeled, controlled storage. Shelf life and retest date come from the supplier's specification.

What is the regulatory status of urolithin A?

FDA's GRAS Notice Inventory lists GRN 791 for urolithin A, notified by Amazentis SA for use in protein shakes, meal replacement beverages, oatmeal, bars and yogurts; it closed on December 20, 2018 with FDA having no questions. Health Canada's Natural Health Products Ingredients Database lists urolithin A as an approved chemical name, with a non-medicinal role as a skin-conditioning agent for topical use only.

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