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Vinpocetine

Vinpocetine suppliers and sourcing guide

Vinpocetine (ethyl apovincaminate) is a synthetic compound made from vincamine, an alkaloid of the lesser periwinkle plant (Vinca minor), or from tabersonine, an alkaloid in Voacanga seeds. According to FDA it does not occur in these or any other plants. It is sold as a white to off-white crystalline powder. Its US status as a dietary supplement ingredient has been questioned by FDA, so buyers should check the regulatory facts below before sourcing it.

See suppliersWhat to ask for on the COA
Also known as
ethyl apovincaminate · apovincaminic acid ethyl ester · Vinca minor derivative
Facts checked
November 2026

Forms and grades of vinpocetine

Suppliers sell different products under the same name. Specify the one you need.

  • Purified vinpocetine (98% or more)

    Crystalline powder, the usual traded form.

  • Vincamine-derived

    Made from vincamine from Vinca minor or related sources.

  • Tabersonine-derived

    Made from tabersonine extracted from Voacanga seeds.

  • Diluted triturations

    Vinpocetine blended onto a carrier so milligram doses can be blended evenly.

What to check on the COA

Compare each result with your own specification when the lot arrives.

Assay (HPLC)
Vinpocetine purity by HPLC against a reference standard, with related substances such as vincamine and apovincamine reported.
Identity
IR spectrum, melting point and HPLC retention time.
Residual solvents
Solvents used in synthesis and purification, against USP <467> or the buyer's limits.
Loss on drying and residue on ignition
Moisture and inorganic residue.
Heavy metals
Lead, arsenic, cadmium and mercury by ICP-MS, checked against the supplier specification and the buyer's own limits.
Microbiology
Total plate count, yeast and mold, coliforms or E. coli, and Salmonella, against the supplier specification.

Storage, lots and expiry

Storage and shelf life

Store sealed in a cool, dry place protected from light. Keep purified material in controlled, labeled storage. Shelf life and retest date are set by the supplier's specification.

Lots and expiry dates

Record the starting material (vincamine or tabersonine), assay and related-substance profile for each lot. Keep lots traceable to finished batches, and keep the regulatory review for this ingredient with the supplier file.

Regulatory status

Facts from regulators and standards bodies, each linked to its source.

  • In September 2016 FDA sought comment on its tentative conclusions that vinpocetine does not meet the definition of a dietary ingredient and is excluded from the definition of a dietary supplement.

    Source: fda.gov (opens in a new tab)

  • In June 2019 FDA issued a safety warning advising pregnant women and women who could become pregnant not to take vinpocetine.

    Source: fda.gov (opens in a new tab)

  • FDA states that vinpocetine is synthetically produced and is not a constituent of Vinca minor, Voacanga or any other plant.

    Source: fda.gov (opens in a new tab)

This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.

Vinpocetine suppliers

Manufacturers and distributors whose own websites say they sell it.

We are checking vinpocetine suppliers now

Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.

Sell vinpocetine? Request a listing

Frequently asked questions

What forms of vinpocetine can brands buy?

Common forms include purified vinpocetine (98% or more), vincamine-derived, tabersonine-derived and diluted triturations. Ask each supplier for the specification sheet of the exact grade they quote.

What should the COA for vinpocetine include?

Expect assay (HPLC), identity, residual solvents, loss on drying and residue on ignition, heavy metals and microbiology, each with its method, specification and result for that lot.

How should vinpocetine be stored?

Store sealed in a cool, dry place protected from light. Keep purified material in controlled, labeled storage. Shelf life and retest date are set by the supplier's specification.

What is the regulatory status of vinpocetine?

In September 2016 FDA sought comment on its tentative conclusions that vinpocetine does not meet the definition of a dietary ingredient and is excluded from the definition of a dietary supplement. In June 2019 FDA issued a safety warning advising pregnant women and women who could become pregnant not to take vinpocetine. FDA states that vinpocetine is synthetically produced and is not a constituent of Vinca minor, Voacanga or any other plant.

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