Agmatine sulfate
Agmatine sulfate suppliers and sourcing guide
Agmatine is the compound formed when the amino acid L-arginine loses its carboxyl group. Commercial agmatine is made by chemical synthesis or by enzymatic decarboxylation of L-arginine, and it is sold as the sulfate salt, which is a stable, white crystalline powder. Brands buy agmatine sulfate for capsules and pre-workout style powders, dosing on agmatine content.
- Category
- Proteins and amino acids
- Also known as
- Agmatine · (4-Aminobutyl)guanidine sulfate · 1-Amino-4-guanidinobutane sulfate
- Facts checked
- November 2026
Forms and grades of agmatine sulfate
Suppliers sell different products under the same name. Specify the one you need.
Crystalline powder
Standard agmatine sulfate powder for capsules and powders.
Synthetic grade
Agmatine sulfate made by chemical synthesis; the supplier's spec should state the route.
Enzymatic grade
Agmatine sulfate made from L-arginine with a decarboxylase enzyme, sometimes sold with a fermentation or natural-source statement.
What to check on the COA
Compare each result with your own specification when the lot arrives.
- Identity
- Infrared spectrum or HPLC retention time matched to a reference standard, plus a sulfate identification test.
- Assay
- Agmatine sulfate purity on a dried basis by HPLC or titration, reported against the supplier specification.
- Related substances
- Residual arginine, putrescine and other impurities by HPLC.
- Loss on drying and residue on ignition
- Moisture by loss on drying and inorganic residue as residue on ignition.
- Heavy metals and microbiology
- Lead, arsenic, cadmium and mercury by ICP-MS, plus total plate count, yeast and mold, E. coli and Salmonella.
Storage, lots and expiry
Storage and shelf life
Store agmatine sulfate in tightly closed, lined containers in a cool, dry place away from light, and reseal opened packs promptly. Shelf life or retest date is set by the supplier's specification; assay, loss on drying and micro are the usual retest points.
Lots and expiry dates
Record assay and production route for each lot and calculate agmatine content from the sulfate salt. Rotate stock FEFO.
Regulatory status
Facts from regulators and standards bodies, each linked to its source.
Health Canada's Workout Supplements monograph lists agmatine, with agmatine sulfate as the source ingredient, among its complementary ingredients, with a maximum of 2 g per day.
Source: webprod.hc-sc.gc.ca (opens in a new tab)The monograph sets label statements for products providing more than 200 mg of agmatine per day.
Source: webprod.hc-sc.gc.ca (opens in a new tab)The EU Novel Food Catalogue entry for agmatine (4-aminobutyl) guanidine sulfate (POL-NF-00094) gives it the status not yet authorised novel food.
Source: ec.europa.eu (opens in a new tab)
This is general information, not regulatory advice. Status differs by country and by how the ingredient is used, so check the rules for your product and market.
Agmatine sulfate suppliers
Manufacturers and distributors whose own websites say they sell it.
We are checking agmatine sulfate suppliers now
Every listing is checked against the supplier’s own website before it goes live, so this list fills in over the coming weeks. The specs and COA checklist above are ready today.
Sell agmatine sulfate? Request a listingFrequently asked questions
What forms of agmatine sulfate can brands buy?
Common forms include crystalline powder, synthetic grade and enzymatic grade. Ask each supplier for the specification sheet of the exact grade they quote.
What should the COA for agmatine sulfate include?
Expect identity, assay, related substances, loss on drying and residue on ignition and heavy metals and microbiology, each with its method, specification and result for that lot.
How should agmatine sulfate be stored?
Store agmatine sulfate in tightly closed, lined containers in a cool, dry place away from light, and reseal opened packs promptly. Shelf life or retest date is set by the supplier's specification; assay, loss on drying and micro are the usual retest points.
What is the regulatory status of agmatine sulfate?
Health Canada's Workout Supplements monograph lists agmatine, with agmatine sulfate as the source ingredient, among its complementary ingredients, with a maximum of 2 g per day. The monograph sets label statements for products providing more than 200 mg of agmatine per day. The EU Novel Food Catalogue entry for agmatine (4-aminobutyl) guanidine sulfate (POL-NF-00094) gives it the status not yet authorised novel food.
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